Sermorelin

Sermorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH), the signal that tells the pituitary gland to release growth hormone. Vivo offers it as a compounded prescription injection, prescribed by a licensed provider after an intake and prepared by a licensed compounding pharmacy.

Yes. Sermorelin is a synthetic peptide made of the first 29 amino acids of human GHRH, the portion that carries its biological activity.

No. Sermorelin is not human growth hormone. It is a GHRH analogue, a different medication, and Vivo does not supply, prescribe or represent it as HGH.

Normally, GHRH from the hypothalamus signals the pituitary gland to release growth hormone. Sermorelin acts at that same step: as a GHRH analogue, it stimulates the pituitary to release the growth hormone your body makes.

Stimulating growth hormone release is what sermorelin does, and it has been measured in people. In one small study of healthy older men, nightly GHRH(1-29) injections increased nocturnal growth hormone release. A hormonal response like that is not the same as a demonstrated wellness outcome.

Vivo doesn't claim it does. Growth hormone is studied in relation to body composition, but a growth hormone response does not establish that compounded sermorelin increases lean muscle in a healthy adult. Training, protein, sleep and nutrition still matter, and your provider can help you look at your goals.

Vivo doesn't claim it does. Research on growth hormone and GHRH-related compounds in specific populations can't, on its own, establish that compounded sermorelin reduces body fat or body weight.

Growth hormone release is closely tied to sleep, which is part of why people ask. That relationship does not establish that compounded sermorelin improves sleep quality or produces deeper sleep. If you're sleeping poorly, tell your provider; it can have causes worth evaluating.

It hasn't been established that compounded sermorelin speeds up exercise recovery. Any study on recovery has to be read for the population, dose and route it actually tested.

There isn't a clinically established timeframe in which compounded sermorelin should be expected to produce a particular body-composition, sleep, energy or recovery outcome. Discuss your goals and your response with your provider.

They act at different steps. Sermorelin signals the pituitary to release growth hormone; HGH is growth hormone itself, supplied directly. That difference in mechanism does not make sermorelin safer, more effective or clinically equivalent to HGH.

Exactly as your prescription and the pharmacy's instructions direct. They explain how to prepare a dose, give a subcutaneous injection, rotate injection sites and dispose of used sharps. Ask your care team if anything is unclear.

At the time your provider prescribes. Timing is part of your individual prescription, so follow its instructions rather than a general rule.

Store it exactly as your prescription label and the dispensing pharmacy's instructions say.

Your provider decides what information is needed to evaluate you, based on your health history. If testing is part of your evaluation, your provider will tell you.

Read the Important Safety Information on this page, and talk with your provider or pharmacist about the side effects that apply to your prescription. Contact your care team about any unexpected symptoms, and seek emergency care for a severe reaction.

Your provider must evaluate your medications and hormone therapies individually. Don't combine prescription hormone therapies without medical review, and tell your provider about any hormone therapy you use.

No. Compounded medications are not FDA-approved, and FDA does not review them for safety, effectiveness or quality before they are marketed.

Yes. Every Vivo protocol is prescription-only. When you complete your intake, a licensed US provider in your state reviews your medical history and, if appropriate, writes the prescription. The compounded medication is then shipped directly to your door.

No prescription is issued, and you are not charged for medication. Entering payment information at checkout authorizes your payment method — it does not capture a charge. A charge is captured only after a provider approves the prescription.

Vivo works with the following independent, state-licensed 503A compounding pharmacy:

VialsRX — 6220 Westpark Drive, Suite 111, Houston, TX 77057 — vials.ai

Services are available across all 50 U.S. states through affiliated providers and our pharmacy partner operating in accordance with applicable state licensure requirements.

Please note that medication availability, formulations, and fulfillment options may vary depending on state-specific pharmacy regulations and dispensing restrictions.

You can cancel a subscription at any time from your account dashboard, or by emailing care@vivoclinic.org. Cancellation takes effect at the end of your current billing period, provided we receive it before that period's order is transmitted to the pharmacy. Once an order has been transmitted to the pharmacy, or compounding has begun, it can't be canceled or refunded — it's being prepared specifically for you. Full details are in our Refund Policy.

Under 5 minutes, online, whenever suits you. There's no appointment and nothing to schedule.

Vivo Clinic serves patients across all 50 U.S. states through our affiliated medical provider, Arora Health & Aesthetics, LLC. Treatment and medication availability may vary depending on provider licensure, state telehealth requirements, and pharmacy dispensing restrictions.