NAD+ Face Cream

A compounded prescription cream containing NAD+ (nicotinamide adenine dinucleotide), prescribed by a licensed provider after an intake and prepared by a licensed compounding pharmacy.

No. Niacinamide (nicotinamide) is a form of vitamin B3 that the body can use to make NAD+. It is a different, smaller molecule with its own research literature, and findings about niacinamide don't transfer to NAD+ cream.

No. Nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) are precursors the body can use to make NAD+. They are different compounds, and research on them isn't evidence for topical NAD+.

As in cells throughout the body, NAD+ takes part in redox reactions involved in energy metabolism and is used by enzymes involved in cellular signaling and responses to DNA damage. Those are roles of the body's own NAD+, not demonstrated effects of applying it to skin.

It depends on the formulation: the molecule, concentration, base, stability and the condition of the skin barrier all matter. How effectively intact NAD+ penetrates human skin from topical formulations is still being studied.

Vivo doesn't claim it does. Compounded topical NAD+ has not been shown in clinical studies to reduce wrinkles or fine lines.

Vivo doesn't claim it does. NAD+ biology in skin cells doesn't establish that applying an NAD+ cream increases collagen, and there isn't product-specific evidence that it does.

Whether compounded topical NAD+ improves firmness or elasticity hasn't been established. Vivo makes no firmness claim for it.

NAD+ and hydration aren't the same thing. Any moisturizing effect would come from the cream base, and Vivo will describe the base only once its complete formulation has been verified with the pharmacy.

Vivo doesn't claim it does. There isn't an established cosmetic outcome, including brightening, for compounded topical NAD+.

Vivo doesn't represent NAD+ Face Cream as a treatment for hyperpigmentation, melasma or any other skin condition. If you have a skin condition, tell your provider; it may deserve its own evaluation.

They are different routes and formulations intended for different treatment contexts: the cream is applied to the skin, and the nasal spray (see the NAD+ Nasal Spray page) is used intranasally. One shouldn't be assumed to produce the effects of the other.

That's a decision for your provider, based on your intake and treatment goals.

Ask your provider. Guidance depends on your prescription, the formulation and the rest of your routine.

Ask your provider. Guidance depends on your prescription, the formulation and the other products you use.

As your prescription directs.

The amount your prescription specifies. Don't change it without talking to your provider.

Follow the storage instructions on your prescription label and from the dispensing pharmacy.

There isn't a clinically established timeline in which compounded NAD+ Face Cream should be expected to produce a particular cosmetic outcome. Individual experiences vary.

No. Compounded medications are not FDA-approved, and FDA does not review them for safety, effectiveness or quality before they are marketed.

Yes. NAD+ Face Cream is available by prescription only. Every order starts with an online medical intake and review by a licensed provider, who determines whether a prescription is clinically appropriate. Patients must be 18 or older and physically located in a state where services are available, both at intake and at each refill. Services are currently available in all 50 US states, subject to state regulation.

A card may be authorized at checkout and is charged only after a provider approves a prescription. If a licensed provider determines the medication is not clinically appropriate, no prescription is issued, no medication ships, and no charge is completed for that medication order.

Provider review is asynchronous by default, based on the written intake. Some states require a synchronous visit (live video or phone) before a provider can prescribe, and a provider may also request one if clinically indicated.

Prescriptions are issued by licensed providers. Medical leadership includes Dr. Sean Arora, M.D., and Dr. Shannon Arora, M.D. Prescriptions are prepared and shipped by a licensed US 503A compounding pharmacy. Vivo Health LLC operates the platform and does not practice medicine or dispense medication.

No. NAD+ Face Cream is a compounded medication prepared by a licensed pharmacy for an individual prescription. Compounded medications are not FDA-approved drug products.